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Silver Labs
☆ Health Testing☆
PRA stands for Progressive Retinal Atrophy. It is a general term for the group of
diseases causing degeneration of the retina, leading to loss of vision. The form of
this disorder in Labradors is prcd (Progressive Rod-Cone Degeneration). This
leads first to the loss of night vision and then to complete blindness of the dog.
The typical onset for this is between age 3 and 5 years of age.

RD/OSD stands for Retinal Dysplasia-retinal folds (RD). Retinal folds can cause
blindness in a dog if not corrected by surgery. OSD (OculoSkeletal Dysplasia) is a
serious inherited syndrome that causes severe condition in which the dogs show
a variety of skeletal malformations, including shortened limbs (dwarfism), and
blindness at an early age; the blindness results from a generalized malformation
of the retina that causes a partial or full retinal detachment and cataracts.

EIC stands for Exercise-Induced Collapse. It is a devastating genetic disorder
causing the affected dog to suffer from loss of muscle control following extreme
exercise. This disorder is caused by a mutation in the Dyamin 1 gene. Because EIC
is a recessive disorder, a dog must have two copies of the mutation in order for
the disease to manifest itself. Typically an affected dog begins to show symptoms
between 5 months and 3 years of age.

DM stands for Degenerative myelopathy is a progressive disease, meaning that
dogs get slowly weaker and weaker over a four to six month period of time
following diagnosis. Degenerative myelopathy usually affects the hind legs first,
but muscle weakness can spread to the front legs as well. Dogs with degenerative
myelopathy may begin to stumble frequently as they become progressively
weaker due to nerve damage. Eventually, dogs with degenerative myelopathy will
lose control of their bladder and bowels. As the disease moves into its final
stages, symptoms of weakness, trembling and stumbling will begin to affect the
front legs as well.  

CNM stands for Centronuclear Myopathy. Puppies are born apparently normal,
however, it quickly becomes evident that there is a problem. The puppy will often
not gain weight due to decreased muscle tone in the esophagus. By age 2 to 5
months the disease has usually progressed to display the full range of symptoms,
including a loss of muscle tone and control, an awkward gait and extreme
exercise in tolerance. This condition gets worse in cold conditions. There is not
cure for CNM, although the dog can live a normal life span, their muscles tissue
will never develop properly.  
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Cystinuria is a genetic defect in which the kidney is not able to process a basic
amino acid, cystine, correctly. Affected dogs are born with this condition but in
most cases it takes many years before things get bad enough that we notice it.
Over time, the unprocessed cystine in the urine clumps together to form stones.
These stones can block the urinary tract. This is a life-threatening condition and
requires surgery.
White Labs